Tamoxifen 

Tamoxifen (Brand name: Nolvadex) is a medication in pill form that interferes with the activity of estrogen (a hormone). Tamoxifen has been used for more than 20 years to treat patients with advanced breast cancer. It is used as additional therapy following primary treatment for early stage breast cancer. In women at high risk of developing breast cancer, Tamoxifen reduces the chance of developing the disease. It is also being studied in the treatment of several other types of cancer. 


What does Tamoxifen do? 

Estrogen promotes the growth of breast cancer cells. Tamoxifen works against the effects of estrogen on these cells. It is often called an "anti-estrogen." As a treatment for breast cancer, the drug slows or stops the growth of cancer cells that are present in the body. As adjuvant therapy, Tamoxifen helps prevent the original breast cancer from returning and also helps prevent the development of new cancers in the other breast. 


Side effects of taking Tamoxifen? 

In general, the side effects of Tamoxifen are similar to some of the symptoms of menopause. The most common side effects are hot flashes and vaginal discharge. Some women experience irregular menstrual periods, headaches, fatigue, nausea and/or vomiting, vaginal dryness or itching, irritation of the skin around the vagina, and skin rash. As is the case with menopause, not all women who take Tamoxifen have these symptoms. 


Who should not take Tamoxifen?

Tamoxifen may make premenopausal women more fertile, but doctors advise women on Tamoxifen to avoid pregnancy because animal studies have suggested that the use of Tamoxifen in pregnancy can cause fetal harm. Women who have questions about fertility, birth control, or pregnancy should discuss their concerns with their doctor. 

The benefits of Tamoxifen as a treatment for breast cancer are firmly established and far outweigh the potential risks. When taken for 5 years, the drug reduces the risk of recurrence of the original breast cancer and also reduces the risk of developing a second primary cancer in the other breast. Patients who are concerned about the risks and benefits of Tamoxifen or any other medications are encouraged to discuss these concerns with their doctor.

More facts are available at the National Cancer Institute.

The information contained above is provided for educational purposes only and is not intended to replace discussions with your physician.

Review - How to Order Tamoxifen from Canada - click here

Tablets available in 10mg and 20mg doses.

Nolvadex - Canada Internet Pharmacy